Team of Prof. Pil Joon Seo (dept. Life Science), Identifying the induction mechanism of Cellular Dedifferentiation
- 자연과학대학
- Hit2596
- 2018-02-09
Team of Prof. Pil Joon Seo (dept. Life Science at SKKU), Identified the induction mechanism of Cellular Dedifferentiation and published the paper on Science signaling (IF: 6.494) on November 28th.
* Cellular dedifferentiation: the already differentiated cells are converted into the undifferentiated state and the cell division ability is restored
Prof. Pil Joon Seo and his colleagues have identified chromatin modifications that specifically regulate the derived process of stem cells, and have identified the action mechanism of these proteins for the first time in the world.
Since the possibility of regeneration into plants with desired characteristics is opened through the enhancement of the dedifferentiation efficiency, the present study suggests that it will contribute greatly to the improvement of the traits of crops in the future.
This study was conducted as the Bio Green 21 project (Plant Molecular Breeding Project) of the RDA and the basic laboratory project of the Korea Research Foundation.
Fig. 1 Callus formation in leaf explants from atxr2 mutant and ATXR2-overexpressing plants.
(A) Callus formation in leaves explanted from young wild-type (Col-0), atxr2-1, atxr2-3, and 35S:ATXR2-MYC plants. Scale bar, 5 mm. n > 30 plants of each genotype. (B) Fresh weight of calli from wild-type (Col-0), atxr2-1, atxr2-3, and 35S:ATXR2-MYC plants. Bars indicate the SE of the mean. *P < 0.05 (Student’s t test). n = 30 calli of each genotype.
(Source: http://stke.sciencemag.org/content/10/507/eaan0316.full)