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- AORC for Mathematics Signed MOU on joint research with Nankai and Tianjin University Centers
- AORC for Mathematics, Nankai University Center for Combinatorics and Tianjin University Center for Applied Mathematics Signed MOU on joint research Algorithm and optimization theory in big data and artificial intelligence, which is leading the 4th industrial revolution, has become increasingly important, so the 'Application Algebra and Optimization Research Center(AORC)' held a Mutual Academic Exchange Agreement(MoU) signing ceremony on research cooperation with 'Center for Combinatorics' of China's Nankai University and 'Center for Applied Mathematics' of Tianjin University on October 23rd at Tianjin University. With the increasing importance of graph theory and combination in algorithms and optimization theories, professor Gi-sang Cheon, the director of the AORC for mathematics, and professor Willian Y. Chen, the director of two research centers in China, intend to expand and develop joint research area of combination and graph theory through this academic exchange agreement. Nankai University was founded in 1919 in Tianjin as the first private university in China. It is famous as the first premier in China, Zhou Enlai (周恩來) and the world-renowned mathematician Shiing-Shen Chern(陳省身) after becoming a public university. The 'Combination Center' established by Professor W.Y. Chen at the Nakai University in 1997 with the support of Tenjin has grown steadily to become a global research center with government support. Currently, 12 full-time faculty members and many visiting researchers and graduate students make active studies. In particular, the journal 'Annals of Combinatorics', which was created at the time of the establishment of the center, is now the representative SCI journal in the field of combinatorics. 'Applied Mathematics Research Center' was founded in Tianjin University by the plan of S.-S. Chern Professor with the support of the Tianjin municipal government in 2012. Professor W. Y. Chen is the head of the Center since its inception, and 50 full-time faculty members are actively studying the application areas of mathematics. In the next few years, more than 50 teachers will be recruited. The center's goal is to develop into a world-class applied mathematics laboratory to facilitate the application of mathematics to science and practical problems.
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- 작성일 2017-11-06
- 조회수 2930
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- Prof. Jung Hoon HAN(dept. of Physics) has published a scholarly book, ‘Skyrmions in Condensed Matter’
- Prof. Jung Hoon HAN has published a scholarly book, ‘Skyrmions in Condensed Matter’, at the request of Spinger, one of the leading publishers in the science publishing industry. The book summarizes some of the most exciting developments that have taken over the last decade regarding topological phenomena in spin-orbit-coupled condensed matter systems. Key topics discussed are the topological origin of anomalous Hall effects in solids, its extension to incorporate spin Hall effects and its quantization, topological phenomena originating from spin texture, topological insulators, and other forms of exotic topological matter. The topics are presented at a pedagogical level accessible to graduate students who finished a course in traditional solid state physics. Concepts originally invented in the context of particle physics, now heavily used in topological condensed matter, are presented at a level easily accessible to scientists without prior training in that discipline. The book provides an introduction and a survey of what underlies the modern theory of topological phenomena driven by spin-orbit coupling. https://link.springer.com/book/10.1007/978-3-319-69246-3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ▶ Introduction This book summarizes some of the most exciting developments that took place over the last decade regarding topological phenomena in spin-orbit-coupled condensed matter systems. Key topics discussed are the topological origin of anomalous Hall effects in solids, its extension to incorporate spin Hall effects and its quantization, topological phenomena originating from spin texture, topological insulators, and other forms of exotic topological matter. The topics are presented at a pedagogical level accessible to graduate students who finished a course in traditional solid state physics. Concepts originally invented in the context of particle physics, now heavily used in topological condensed matter, are presented at a level easily accessible to scientists without prior training in that discipline. The book provides an introduction and a survey of what underlies the modern theory of topological phenomena driven by spin-orbit coupling. ▶ Keywords Anomalous Hall Effect Berry Phase Quantized Spin Hall Effect Quantum Pumping Soliton Spin Hall Effect Spin-orbit Interaction Spinor Bose-Einstein Condensate Topological Hall Effect Topological Insulator ▶ Authors and affiliations Jung Hoon Han 1 1.Department of PhysicsSungkyunkwan UniversitySuwonKorea (Republic of) ▶ Bibliographic information DOI https://doi.org/10.1007/978-3-319-69246-3 Copyright Information Springer International Publishing AG 2017 Publisher Name Springer, Cham eBook Packages Physics and Astronomy Print ISBN 978-3-319-69244-9 Online ISBN 978-3-319-69246-3 Series Print ISSN 0081-3869 Series Online ISSN 1615-0430 About this book
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- 작성일 2017-10-30
- 조회수 3089
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- Identification of new metastasis of intractable triple breast cancer
- Sungkyunkwan University Professor Park Seok-Hee Research Team (joint research) identified the mechanism of metastasis of metastatic breast cancer including triple-negative breast cancer, collaborating with the Advanced Institutes of Convergence Technology and Gangnam Severance Hospital. It was posted on Nature Cell Biology (IF: 20.06), published online September 11. It is the first time in the world to identify that the A20 protein, which regulates inflammation and immunity, mediates the metastasis of triple negative breast cancer by inducing multiple mono ubiquitination of Snail1 transcription factors associated with cancer cell migration and invasion. This study revealed that A20 protein specifically binds to Snail1 protein and mono ubiquitination of three lysine amino acids of Snail1 protein. This mono-ubiquitination of Snail1 induces a decrease in mutual binding to GSK3β, which phosphorylates Snail1 protein, which ultimately proved to be able to induce metastasis by increasing the stability of Snail1 protein in the nucleus. In addition, triple negative breast cancer cell lines inhibited the expression of A20, suggesting that cancer cell resistance to doxorubicin and docetaxel, which are common breast cancer treatments, is reduced. “As this study provides theoretical basics of development of a protein interaction blocker that specifically inhibits the interaction between the A20 protein and the Snail1 protein, or the development of a mono ubiquitination inhibitor of Snail1, it will be possible to develop a new cancer suppressor for metastatic breast cancer including triple negative breast cancer in the future”, Professor Park said. The results of this study were published in the September 11 online edition of Nature Cell Biology (IF Biochemistry, IF: 20.06), the leading professional journal in molecular and cellular biology.
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- 작성일 2017-10-24
- 조회수 2974
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- Science camp sponsored by Professor Kim Seung Chul of Life Science Department
- The science camp, which aims to stimulate interest in life sciences through experiential activities for young people and to help them design their careers, was hosted by Professor Kim Seung Chul of the Department of Biological Sciences on August 10-11th. The camp, which was attended by 20 students from Yushin High School, carried out four activities: lecturing, experimentation, analysis, and microscopic observation with 7 graduate students in Plant Molecular System Lab. - Lecture: Professor Kim Seung-Chul, Plant evolution and system - Experiments: DNA extraction, polymerase chain reaction, gel electrophoresis, PCR product purification, - Analysis: contig assembly, phylogenetic analysis, - Microscopic observation of plant by scanning electron microscope (SEM) The camp was a meaningful time for students to indirectly experience biological sciences, especially ‘investigation of plant evolution using DNA’.
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- 작성일 2017-10-12
- 조회수 2797
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- SKKU researchers develop space experiment equipment, go to International Space Station
- A large space experiment device made by Korean researchers is loaded into the space on a rocket. Sungkyunkwan University announced that a silicon charge detector (SCD) produced by Park Il-heung, a professor of Department of Physics, will be sent to the International Space Station (ISS) at the Kennedy Space Center in the United States at 1:31 pm (local time). The spacecraft will head to space on Space X's rocket 'Dragon'. It will be installed in an external module of the space station and will perform space missions for at least three years. Silicon charge detector is a device for precisely measuring the components of 'cosmic rays', particles that fall from space to Earth. It is made using semiconductor sensor technology. The ship was first discovered in 1912, but its origins and propagation processes have not been identified for more than 100 years. NASA is conducting a space experiment called 'ISSCREAM' to measure high-energy spacecraft. Korea, the United States, France and Mexico are participating in the experiment. According to Sungkyunkwan University, this silicon charge detector plays a key role in ISSCREAM. It is made of pure domestic technology and has an area of 1 ㎡ and a weight of 150 ㎏, which is the maximum size used in space. Four layers of silicon sensors measure the cosmic ray components (accuracy 99%). This detector was developed by Sungkyunkwan University in cooperation with Korea Electronics and Telecommunications Research Institute and small and medium enterprises. The whole process was conducted in Korea. Professor Park said, "This is the first time to install cutting-edge equipment from Korea for the space experiment of the International Space Station." This is a case in which the equipment takes charge of main-mount equipment of NASA's main space project and participates in practical, core, and companion status."
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- 작성일 2017-09-15
- 조회수 2821
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- Prof. Do Hyun RYU Develops the First Catalytic Asymmetric Synthesis of 2,5-dihydrooxepine
- A research team led by Prof. Do Hyun RYU (Dept. of Chemistry) has developed the first catalytic synthetic method of chiral 2,5-dihydrooxepine. 2,5-Dihydrooxepine, seven-membered cyclic compound containing oxygen atom, is a structural core of many important natural products. Therefore, a variety of synthetic methods have been widely developed for several decades. However, there has been no example of catalytic asymmetric synthesis of 2,5-dihydrooxepines and multiple synthetic steps were required to prepare corresponding starting materials. The research team developed asymmetric synthetic method of highly functionalized 2,5-dihydrooxepine with chiral Lewis acid catalyst through cyclopropanation/retro-Claisen rearrangement tandem reaction to give good yields and high enantioselectivity. Developed methodology exhibits excellent atom economy because this utilizes simple starting materials and nitrogen gas (N2) is the only by-product. Since there are various bioactive natural products which possess dihydrooxepine as a key structure, chiral 2,5-dihydrooxepine derivatives synthesized with developed method are expected to be used in bio- or medicinal chemistry fields. Prof. RYU said "the value of this work is to synthesize enantioenriched 2,5-dihydrooxeines from simple starting materials using catalyst. Furthermore, this work is highly valuable because this suggests experimental results to support computational calculation data about reaction mechanism of retro-Claisen rearrangement of cyclopropane to 2,5-dihydrooxepine." This research was published in the Angewandte Chemie International Edition (IF : 11.709) as of April 18th, with the title of "Catalytic Enantioselective Synthesis of 2,5-Dihydrooxepines" (doi: 10.1002/anie.201700890). This work was selected as a Very Important Paper (VIP) and front cover page of July 17th.
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- 작성일 2017-09-11
- 조회수 2894
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- Prof. Jong San CHANG Develops a Study on Selective Nitrogen Capture by Porous Hybrid Materials
- Prof. Jong San CHANG (dual-appointed professor, Dept. of Chemistry, SKKU and KRICT) and his colleagues have recently published an important article, titled “Selective nitrogen capture by porous hybrid materials containing accessible transition metal ion sites’’ in Nature Materials (doi:10.1038/nmat4825). It is known that selective dinitrogen binding to transition metal ions mainly covers two strategic domains: the biological nitrogen fixation, catalyzed by metalloenzyme nitrogenases, and the adsorptive purification of natural gas and air. Many transition metal-dinitrogen complexes have been envisaged for biomimetic nitrogen fixation to produce ammonia. Inspired by this concept, Prof. CHANG's group developed the first-ever adsorbent, a mesoporous Metal-Organic Framework (MOF) material containing accessible Cr(III) sites, able to thermodynamically capture N2 over CH4 and O2. This study resulted from cooperative international research, mainly between the research group for nanocatalysts at KRICT and several groups at the National Center for Scientific Research (CNRS) in France. The study presents a major breakthrough in the domain of the selective capture of nitrogen (here N2 mixed with CH4 and O2) using a porous hybrid solid, called a metal-organic framework (MOF), which contains accessible chromium (III) ion sites. The selective adsorption of N2 is a strategic issue, with the related applications, such as the upgrading of natural gas (for the production of pipelined natural gas (PNG) and compressed natural gas (CNG) as alternative fuels) and the purification of air being amongst the most critical challenges facing the industry today. For the moment, the discovery of a porous adsorbent sufficient for such purposes had not yet been achieved because these solids typically exhibit a better affinity for gases such as CH4 or O2 than N2. In this context, Prof. CHANG's group has first introduced the utilization of the concept of cationic unsaturated sites (CUS) for generating drastic changes in host-guest interactions (a general problem in materials science), which is useful to induce an unprecedented affinity for N2 with respect to other gases, far above the performances of materials currently used for the target application. The porous adsorbent material that combines a high selective adsorption, large uptake, easy regeneration, excellent recyclability, and good chemical/thermal stability offers a unique opportunity to achieve highly-efficient N2 capture that is difficult to attain using conventional approaches. From the results, they could identify a clear and striking advance in fundamental understanding or material design. They evidenced the unique property of this solid through a multidisciplinary approach combining state-of-the-art experimental and computational methods. This included structural aspects, infrared spectroscopy, equilibrium and breakthrough adsorption experiments and quantum/force field-based molecular simulations. Inspired by biomimetic and metal dinitrogen chemistry concepts, this multidisciplinary fundamental study revealed that designing MOFs with unsaturated metal sites into their cages offers a unique opportunity to achieve unprecedented, highly efficient N2 capture. It is believed that this publication will pave the way towards unprecedented adsorption-based technologies in the fields of energy, environment, medicine and catalysis by pushing the limits of our current knowledge on porous materials chemistry. In addition to this, the manipulation of multifunctional MOFs possessing both selective N2 binding and catalytic sites may propel forward progress in developing future enzymatic catalysts for N2 fixation, which is a dream of chemists, to produce nitrogen-containing chemicals. Source: http://www.skku.edu/eng_home/campus/skk_comm/news_view.jsp?bName=board_news&bCode=1&boardNum=2381
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- 작성일 2017-09-07
- 조회수 3157
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- Taller People Are Thinner, a Study by Prof. Beom Jun KIM
- If the human body is stretched in three directions of width, length and height, the weight of a human body is proportional to the cube of its height. However, this is not valid in reality, and the body-mass index (BMI) is often calculated from the weight divided by the square of the height. From such definition of the BMI, Prof. Beom Jun KIM has shown that the waist circumference of a human is not proportional to the height, but proportional to the square root of the height. In other words, if the body-mass index is the same, the taller person is thinner. “This is the reason why many fashion models are tall,” Prof. KIM says. By analyzing the data of the length and weight of a variety of fishes, whales, and quadrupedal land mammals, Prof. KIM has shown that weight is proportional to the square of the height only for humans. In the case of other animals, the weight is proportional to the cube of the height. He presumed the reason why the calculation of the body-mass index of a human differs from that of other animals is that humans are bipedal, standing and walking upright. From this, he predicted that in the case of infants who cannot walk yet, their weight should be proportional to the cube of their height, but children older than about one year old should have a weight proportional to the square of their height. This prediction was tested for data from Sweden, Korea, and the World Health Organization, and was confirmed to be correct. If we consider the human body as the form of a simple cylinder and apply the condition that the torque by gravity and the torque by muscle must be in balance, we can show that the weight of a human should be proportional to the square of the height using Newtonian mechanics of physics. Prof. KIM also said that if we measure the size of the pelvis and the height from human fossil records, we will be able to deduce the time when mankind started to walk upright. Figure 1. Graphs of the relationship between the height (H) and the weight (M) of pale chub fish, whales and land mammals. All three graphs show that the animals’ weight is proportional to the cube (p = 3) of the height. For land animals, the height (H) can be measured in two ways: shoulder height and head-to-tail length. Both ways to measure the height meet the relationship (M is proportional to the cube of H). Figure 2. Graphs of the relationship between the height (H) and the weight (M) of children from Sweden and Korea. In this figure, the purple dots represent infants younger than one year old, and the orange dots represent children older than one year old. At one year of age, the time when a child begins to walk, the relationship between the height and weight is changed. Before one year, the weight is close to the cube of the height as with the other animals in Figure 1 above, but after one year, weight is close to the square of the height. Figure 3. A simple model of a human body. By applying the equilibrium condition of the torque by gravity (Fg) and the torque by muscle (Fm), we can show that the weight of a human being should be proportional to the square of the height. Figure 4. According to the body-mass index calculation method, the waist circumference of a human being is proportional to the square root of the height. The figure shows how body somatotype is changed according to the height if the body-mass index is the same. The taller the person is, the thinner it becomes. In the figure, when the height doubles, the waist circumference is about 1.4 times (or the square root of 2) smaller.
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- 작성일 2017-08-21
- 조회수 2999
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- [SKKU People Now] President of Alumni Reunion of SKKU, Shin Yoon-ha (58, Biological Sciences)
- If you are a student of Sungkyunkwan University, you might have listened to a cheerful melody; 'Sungkyunkwan University! Of 600years tradition~’ Like the lyrics, our school has a long history. As a result, many seniors have entered various fields. There is a place that connects the seniors and juniors who are active in their respective fields. It is 'Sungkyunkwan University Alumni Reunion'. We met with Shin Yoon-ha (58, Biological Sciences), President of Alumni Reunion of SKKU, which creates a strong link between seniors and juniors. The way president Shin walked He was born in 1938 in Incheon, Kyounggi Province. Because of economic difficulties, he started working part-time since he was a junior high school student. Even though he was suffering, he did not give up his studies and eventually he entered Sungkyunkwan University. After graduating from university, he worked for a health center, transport company, and started a construction business. He returned to school after working in various jobs. He came to the school and was in charge of three vice president of management forum, founder of forum golf meeting, global center construction executive, scholarship foundation board, and branch council chairperson. He has held various positions and helped the reunion work for about 15 years. Thanks to this achievement, he became president of the 35th general meeting in 2016. As 35th president of Alumni Reunion Sungkyunkwan University Alumni Reunion was established on August 31, 1951. The purpose of the general meeting is to promote fellowship among the alumni and school development. In order to accomplish the above objectives, the scholarship project, promotion of fellowship among members, organization of membership list and newsletter publishing business have been conducted. President Shin Yoon-ha compared the total alliance to "clay". "The purpose of the alliance is to tie alumni scattered like sand, into clay. Just because we entered the same school and shared the history of the same school, we are already a family. It is a great strength for each other in society if we have the same kind of help and support. In addition, with the help of your seniors, if your name is widely known by the younger people in the future, the school's reputation will increase. I think this is a tremendous benefit in terms of social recognition. Therefore, it is a place where tying every single piece of sand to make clay to contribute to the development of the school. " Era of ‘Global SKKU’ has opened On January 11, 2017, President Shin Yoon-ha announced the launch of the Global Sungkyun Scholarship Foundation. Global Sungkyun Scholarship Foundation provides full scholarships to foreign students and living expenses for outstanding SKKU students studying abroad to top universities. President Shin Yoon-ha explained the purpose of the Global Sungkyun Scholarship Foundation as follows. "The purpose of the Global Sungkyun Scholarship Foundation is to help foreign students studying in SKKU and SKKU students in foreign countries to study hard. I know that many foreign students attend Sungkyunkwan University but do not receive sufficient financial support. I wanted to help them do not suffer from tuition problems and work hard to learn. I also wanted to create an environment where SKKU students could concentrate on their studies without worrying about living expenses of going abroad. Furthermore, if Sungkyunkwan University's reputation is improved internationally, would not it be good for the student and the school to be good at selling? (Laughter) "The Global Sacrifice Scholarship Foundation is aiming for a 10 billion won scholarship fund. He already donated 1 billion won to the Global Sungkyun Scholarship. When asked how he was pleased with such a large amount, he said, "I wanted to help my juniors focus on their studies without worrying about money since I have experienced it already. I think that as the president of the alumni reunion, I should try to lead the development of the school. The money is for my juniors and school. (laugh)". Advice for juniors I would like students to look far in their lives rather than to be in front of their eyes. I hope students to plan in long term, what I can do better than others and what is promising. Do not forget to study, the main responsibility of the student, and study hard. Studying can be the key to opening the future of students. I would like students to be a good person in the future, equipped with a high level of perspective and intelligence. Thank you."
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- 작성일 2017-08-08
- 조회수 3102
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- President RYU Deokhee of Kyungdong Pharmaceutical, donated for Songcheon Medical Research Fund
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President RYU Deokhee of Kyungdong Pharmaceutical (Chemical 56 / Honorary Chairman of General Meeting) donated 200 million KRW for Songcheon Medical Research Fund
On June 19, 2017, Ryu Deokhee, President of Kyungdong Pharmaceutical (Chemical 56 / Honorary Chairman of the General Association) visited the Office of the President of the Humanities and Social Sciences Campus and delivered 200 million won of Songcheon Medical Research Fund. On this day, Chung Kyusang, President of SKKU, Hyun Sunhae, Vice President of SKKU, Lee Kyunghoon, Vice Dean of School of Medicine and related officers attended the ceremony and expressed thanks for President Ryu Deokhee's support for the development of school. Since 2005, Honorary Chairman Ryu Deokhee has contributed 2 billion KRW to the Songcheon Medical Research Fund to support the academic promotion and research activities of the School of Medicine. The cumulative donation amount to his alma mater is 9.1 billion KRW. At the research funding ceremony, honorary chairman Ryu Deok-hee said, "I want to contribute a little to improving the research capacity of medical schools. I hope that it will lead to the achievement of excellent human resources development with active research activity. I want to continue to help my school and medical school continue to develop further. " -
- 작성일 2017-08-01
- 조회수 3010